Neuroendocrinology, Volume 181: THE NORMAL NEUROENDOCRINE SYSTEM (Progress in Brain Research) by Luciano Martini, George Chrousos, Fernand Labrie, Karel Pacak, Donald W. Pfaff

Neuroendocrinology, Volume 181: THE NORMAL NEUROENDOCRINE SYSTEM (Progress in Brain Research)



Download Neuroendocrinology, Volume 181: THE NORMAL NEUROENDOCRINE SYSTEM (Progress in Brain Research)




Neuroendocrinology, Volume 181: THE NORMAL NEUROENDOCRINE SYSTEM (Progress in Brain Research) Luciano Martini, George Chrousos, Fernand Labrie, Karel Pacak, Donald W. Pfaff
Language: English
Page: 299
Format: pdf
ISBN: 0444536175, 9780444536174
Publisher: Elsevier Science

From the Back Cover

Neuroendocrinology is a discipline which originated 50 years ago when it was postulated that the hypothalamus might control the anterior pituitary gland through the synthesis of specific Releasing and Inhibiting Hormones. It soon became evident that the brain was responsible for the biosynthesis of many neuropeptides which acted as neurotransmitters, operating in strict cooperation with acetylcholine, the catecholamines and serotonin.

It was discovered that many recognized neuropeptides are directly produced in several peripheral tumors, facilitating their exact localization, suggesting the appropriate therapies and dictating their prognosis. Synthetic neuropeptides together with antiestrogens and antiandrogens are now considered crucial for the treatment of hormone-dependent cancers such as breast and prostate malignancies. Recent work has revealed that neuropeptides and steroid hormones may play a role in the treatment of the most common neurodegenerative diseases of the brain, such as Alzheimer's.

Volumes 181 and 182 Research provide a comprehensive picture of the current field of neuroendocrinology, taking into account its two articulations: basic sciences (volume 181) and clinical applications (volume 182).

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